Case Studies
/ Congenital Adrenal Hyperplasia (CAH) Gene Therapy Trial
Accelerating Patient Recruitment for a CAH Gene Therapy Trial
Patient Outreach, Data Management & Analytics
About the project
MBL Health partnered with a U.S. biotech sponsor to accelerate patient recruitment for a Congenital Adrenal Hyperplasia (CAH) gene therapy clinical trial.
We developed a scalable patient recruitment ecosystem designed to identify and engage eligible patients, streamlining recruitment and improving study site efficiency.
Recruiting for a rare disease gene therapy is uniquely complex.
The sponsor required a scalable recruitment strategy capable of expanding patient reach while delivering high-quality, trial-ready referrals.
Low awareness of gene therapy clincal trial options
Complex eligibility criteria increasing screening drop-off
Reliance on traditional site-based recruitment
An Integrated Patient Recruitment Ecosystem
We launched omnichannel digital outreach campaigns that identified and engaged patients living with CAH, creating a scalable recruitment pipeline that supported patient enrolment into the CAH gene therapy trial
IRB-approved Patient Education
Developed IRB-approved educational materials that translated complex CAH and gene therapy concepts into clear, accessible language for patients and caregivers.
Digital Patient Experience
Designed and launched a study website with integrated online pre-screening, providing a seamless patient journey from education to study referral.
Omnichannel Outreach
Launched targeted campaigns across search, social media and patient communities to identify and engage individuals living with CAH.
04 — Precision Patient Recruitment
Finding eligible patients beyond traditional investigator networks
Our recruitment strategy combined real-time campaign optimisation, patient behaviour insights and recruitment analytics to continuously improve referral quality throughout the study.
Data-driven optimization
Continuously refined patient journeys, campaign performance and eligibility pathways using real-time recruitment data.
DupCheck+ Verification
Automatically detected duplicate registrations to improve recruitment quality and trial integrity.
JAVIS
Centralised patient data, recruitment analytics and referral workflows, providing sponsors with real-time operational visibility.
Outcomes that moved the trial forward.
430+
Patients recruited through digital campaigns
MBL Health's digital-first approach gave us a quality patient pipeline our traditional channels couldn't match — and at a pace our timeline required.
Clinical Operations Lead
Biotech sponsor, CAH program